LABORATORY SAFETY QUIZ
Email:_____________________ Supervisor: ____________________ Date: (mm/dd/yyyy) ___________
Last Name: __________________ First Name: ____________________ Company/Dept. ______________
1. What is the min
imum PPE required when handling chemicals in the lab:
a. Lab coat, nitrile gloves, safety glasses, face shield and closed toe/heel shoes
b. Lab coat, nitrile gloves, safety glasses and closed toe/heel shoes
c.
Nitrile gloves, safety glasses and closed toe/heel shoes
d. Respirator, face sh
ield, tyvex coveralls and nitrile gloves
2. For any emergency in the laboratory, you should:
a. Call Security at 437-8600
b. Pull the fire alarm
c. Go to your rally point
d. Rinse for 15 minutes
3. ___ T ___F Chemicals should be stored based upon compatibility
4.
___ T ___F If a chemical is rated 3 or greater in GHS the material is an HPM(Hazardous Production
Material) and may require a lab specific SOP(Standard Operating Procedure).
5.
Which is not applicable when responding to a spill of >1 pint of a hazardous or unknown chemical:
a. Call Security
b. Notify others in the area
c. Beginning cleaning up while waiting for ERTs
d. Barricade area
6.
Which is not defined as a characteristic of hazardous waste?
a. Ignitable (FP < 140F)
b.
Slimey, sticky and stinky
c. Reactive
d. Toxic
e.
Corrosive (pH < 2 and >12.5)
7.
___ T ___F A “Buddyis Required when working with high hazard materials, Required to call Security in
case of emergency and required to assist co-workers during emergency
8. ___ T ___F Hydrofluoric acid burns may not be apparent for up to 24 hours
9. ___ T ___F When diluting acid, always add acid to water
2017
-
LABORATORY SAFETY QUIZ
2017
10. Which of the following does not apply when a lab worker is splashed with a corrosive chemical:
a. Rinse using emergency shower for at least 15 minutes
b. Remove contaminated clothing
c. Treat burn area with calcium gluconate
d. Call Security at 437-8600
Answer the following questions using the SDS for Tetrahydrofuran (attached after quiz questions):
11.
What is the correct NFPA Codes for THF?
12. What is the flash point?
a. -40 C
b. -17 C
c. 0 C
d. 10C
13. Which is not a hazard statement for THF?
a.
Harmful if swallowed
b. Causes skin irritation
c. Causes severe skin burns and eye damage
d. Suspected of causing cancer
14. Which is not listed as a precaution for Handling and Storage”?
a. Recommended storage temperature: 2-8 C
b. Air and moisture sensitive
c. Store under inert gas
d.
Dry residue is explosive
a. 2-3-0
b.
1-1-0
c.
3-2-4
d.
1-2-1
15. What section of the SDS contains the OSHA PEL (8 hour Permissible Exposure Limit) for THF?
a.
Section 8: Exposure Control /Personal Protection
b.
Section 9: Physical and Chemical Properties
c.
Section 11: Toxicological Information
d.
Section 15: Regulatory Information
Aldrich - 437727
Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com
Safety Data Sheet
Version 4.5
Revision Date 12/18/2012
Print Date 08/05/2013
1. PRODUCT AND COMPANY IDENTIFICATION
Product name
:
Tetrahydrofuran-d
8
Product Number
:
437727
Brand
:
Aldrich
Supplier
:
Sigma-Aldrich
3050 Spruce Street
SAINT LOUIS MO 63103
USA
Telephone
:
+1 800-325-5832
Fax
:
+1 800-325-5052
Emergency Phone # (For
both supplier and
manufacturer)
:
Preparation Information
:
Sigma-Aldrich Corporation
Product Safety - Americas Region
1-800-521-8956
2. HAZARDS IDENTIFICATION
Emergency Overview
OSHA Hazards
Flammable liquid, Harmful by ingestion., Irritant, Carcinogen
Target Organs
Central nervous system, Liver, Kidney
GHS Classification
Flammable liquids (Category 2)
Acute toxicity, Oral (Category 4)
Skin irritation (Category 2)
Eye irritation (Category 2A)
Carcinogenicity (Category 2)
GHS Label elements, including precautionary statements
Pictogram
Signal word
Danger
Hazard statement(s)
H225
Highly flammable liquid and vapour.
H302
Harmful if swallowed.
H315
Causes skin irritation.
H319
Causes serious eye irritation.
H351
Suspected of causing cancer.
Precautionary statement(s)
P210
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P281
Use personal protective equipment as required.
P305 + P351 + P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing.
Other hazards
Aldrich - 437727
Page 2 of 7
May form explosive peroxides.
HMIS Classification
Health hazard:
2
Chronic Health Hazard:
*
Flammability:
3
Physical hazards:
0
NFPA Rating
Health hazard:
2
Fire:
3
Reactivity Hazard:
0
Potential Health Effects
Inhalation
May be harmful if inhaled. Causes respiratory tract irritation.
Skin
Harmful if absorbed through skin. Causes skin irritation.
Eyes
Causes eye irritation.
Ingestion
Harmful if swallowed.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Synonyms
:
Deuterated tetrahydrofuran
Octadeuterotetrahydrofuran
Formula
:
C
4
D
8
O
Molecular Weight
:
80.16 g/mol
Component
Concentration
Tetrahydrofuran-d8
CAS-No.
1693-74-9
-
4. FIRST AID MEASURES
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a
physician.
5. FIREFIGHTING MEASURES
Conditions of flammability
Flammable in the presence of a source of ignition when the temperature is above the flash point. Keep away from
heat/sparks/open flame/hot surface. No smoking.
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Hazardous combustion products
Hazardous decomposition products formed under fire conditions. - Carbon oxides
Further information
Use water spray to cool unopened containers.
Aldrich - 437727
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6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all
sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive
concentrations. Vapours can accumulate in low areas.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in
container for disposal according to local regulations (see section 13).
7. HANDLING AND STORAGE
Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
Use explosion-proof equipment. Keep away from sources of ignition - No smoking. Take measures to prevent the build
up of electrostatic charge.
Conditions for safe storage
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed
and kept upright to prevent leakage.
Recommended storage temperature: 2 - 8 °C
Store under inert gas. hygroscopic Dry residue is explosive.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Components with workplace control parameters
Components
CAS-No.
Value
Control
parameters
Basis
Tetrahydrofuran-
d8
1693-74-9
TWA
50 ppm
USA. ACGIH Threshold Limit Values (TLV)
Remarks
Central Nervous System impairment Upper Respiratory Tract irritation Kidney damage Confirmed
animal carcinogen with unknown relevance to humans Danger of cutaneous absorption
STEL
100 ppm
USA. ACGIH Threshold Limit Values (TLV)
Central Nervous System impairment Upper Respiratory Tract irritation Kidney damage Confirmed
animal carcinogen with unknown relevance to humans Danger of cutaneous absorption
TWA
200 ppm
590 mg/m3
USA. Occupational Exposure Limits (OSHA) - Table Z-1
Limits for Air Contaminants
The value in mg/m3 is approximate.
TWA
200 ppm
590 mg/m3
USA. OSHA - TABLE Z-1 Limits for Air Contaminants -
1910.1000
STEL
250 ppm
735 mg/m3
USA. OSHA - TABLE Z-1 Limits for Air Contaminants -
1910.1000
TWA
200 ppm
590 mg/m3
USA. NIOSH Recommended Exposure Limits
ST
250 ppm
735 mg/m3
USA. NIOSH Recommended Exposure Limits
Aldrich - 437727
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Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose
combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to engineering controls. If the
respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components
tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Hand protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching
glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in
accordance with applicable laws and good laboratory practices. Wash and dry hands.
Eye protection
Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU).
Skin and body protection
Complete suit protecting against chemicals, Flame retardant antistatic protective clothing, The type of protective
equipment must be selected according to the concentration and amount of the dangerous substance at the specific
workplace.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of
workday.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance
Form
clear, liquid
Colour
colourless
Safety data
pH
no data available
Melting
point/freezing point
Melting point/range: -106 °C (-159 °F) - lit.
Boiling point
65 - 66 °C (149 - 151 °F) - lit.
Flash point
-17 °C (1 °F) - closed cup
Ignition temperature
321 °C (610 °F)
Auto-ignition
temperature
no data available
Lower explosion limit
1.8 %(V)
Upper explosion limit
11 %(V)
Vapour pressure
no data available
Density
0.985 g/mL at 25 °C (77 °F)
Water solubility
soluble
Partition coefficient:
n-octanol/water
no data available
Relative vapor
density
no data available
Odour
no data available
Odour Threshold
no data available
Evaporation rate
no data available
10. STABILITY AND REACTIVITY
Aldrich - 437727
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Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
Vapours may form explosive mixture with air.
Conditions to avoid
Heat, flames and sparks. Extremes of temperature and direct sunlight.
Materials to avoid
Oxidizing agents
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides
Other decomposition products - no data available
11. TOXICOLOGICAL INFORMATION
Acute toxicity
Oral LD50
LD50 Oral - rat - 1,650 mg/kg
LD50 Oral - guinea pig - 2,300 mg/kg
Inhalation LC50
LC50 Inhalation - rat - 3 h - 21000 ppm
Remarks: Drowsiness Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhoea.
Dermal LD50
no data available
Other information on acute toxicity
LD50 Intraperitoneal - rat - 2,900 mg/kg
LD50 Intraperitoneal - mouse - 1,900 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Limited evidence of carcinogenicity in animal studies
IARC:
No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
NTP:
No component of this product present at levels greater than or equal to 0.1% is identified as a
known or anticipated carcinogen by NTP.
OSHA:
No component of this product present at levels greater than or equal to 0.1% is identified as a
carcinogen or potential carcinogen by OSHA.
Reproductive toxicity
no data available
Teratogenicity
Aldrich - 437727
Page 6 of 7
no data available
Specific target organ toxicity - single exposure (Globally Harmonized System)
no data available
Specific target organ toxicity - repeated exposure (Globally Harmonized System)
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation
May be harmful if inhaled. Causes respiratory tract irritation.
Ingestion
Harmful if swallowed.
Skin
Harmful if absorbed through skin. Causes skin irritation.
Eyes
Causes eye irritation.
Signs and Symptoms of Exposure
Central nervous system depression, Cough, chest pain, Difficulty in breathing, Exposure to high airborne concentrations
can cause anesthetic effects., To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
Synergistic effects
no data available
Additional Information
RTECS: Not available
12. ECOLOGICAL INFORMATION
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
PBT and vPvB assessment
no data available
Other adverse effects
no data available
13. DISPOSAL CONSIDERATIONS
Product
Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material
is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed
professional waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
DOT (US)
UN number: 2056 Class: 3 Packing group: II
Proper shipping name: Tetrahydrofuran
Reportable Quantity (RQ): 1000 lbs
Marine Pollutant: No
Poison Inhalation Hazard: No
Aldrich - 437727
Page 7 of 7
IMDG
UN number: 2056 Class: 3 Packing group: II EMS-No: F-E, S-D
Proper shipping name: TETRAHYDROFURAN
Marine Pollutant: No
IATA
UN number: 2056 Class: 3 Packing group: II
Proper shipping name: Tetrahydrofuran
15. REGULATORY INFORMATION
OSHA Hazards
Flammable liquid, Harmful by ingestion., Irritant, Carcinogen
SARA 302 Components
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold
(De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards
Fire Hazard, Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
Tetrahydrofuran-d8
CAS-No.
1693-74-9
Revision Date
1993-04-24
Pennsylvania Right To Know Components
Tetrahydrofuran-d8
CAS-No.
1693-74-9
Revision Date
1993-04-24
New Jersey Right To Know Components
Tetrahydrofuran-d8
CAS-No.
1693-74-9
Revision Date
1993-04-24
California Prop. 65 Components
This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other
reproductive harm.
16. OTHER INFORMATION
Further information
Copyright 2012 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies for internal use only.
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a
guide. The information in this document is based on the present state of our knowledge and is applicable to the
product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the
product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or
from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for
additional terms and conditions of sale.